MolNFT v1 · #173927 · protein
Circular permutant of ribosomal protein S6, P54-55 truncated, L21A mutant.
7BFE · 30S ribosomal protein S6,30S ribosomal protein S6: “Circular permutant of ribosomal protein S6, P54-55 truncated, L21A mutant.”. X-ray diffraction, 1 ligand (IOD), 6 pockets (best druggability 0.40). MolNFT v1 #173927 on GenesisL1…
- PDB
- 7BFE
- Type
- protein
- Length
- 507 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 30S ribosomal protein S6,30S ribosomal protein S6
- UniProt
- Q5SLP8
- Ligands
- IOD
- Pockets
- 6 · best druggability 0.40
Structure
x-ray diffraction · 4 distinct chains · 34% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, E | 30S ribosomal protein S6,30S ribosomal protein S6 | protein | 83 | 35% helix, 37% strand | Q5SLP8 |
| B | 30S ribosomal protein S6,30S ribosomal protein S6 | protein | 86 | 34% helix, 37% strand | Q5SLP8 |
| C, F | 30S ribosomal protein S6,30S ribosomal protein S6 | protein | 85 | 34% helix, 38% strand | Q5SLP8 |
| D | 30S ribosomal protein S6,30S ribosomal protein S6 | protein | 85 | 34% helix, 39% strand | Q5SLP8 |
Ligands and binding sites
- IOD · Iodide ion · ion · 6 copies · chains A, B, C, D, E, F
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 71 | 0.40 | 0.79 | 18 | empty |
| 2 | 122 | 0.36 | 0.73 | 25 | empty |
| 3 | 101 | 0.35 | 0.74 | 16 | IOD |
| 4 | 66 | 0.29 | 0.73 | 16 | empty |
| 5 | 66 | 0.28 | 0.73 | 13 | IOD |
Interfaces
5 interfaces between chains.
- C–D · 712 Ų buried · 18 hydrogen bonds · protein-protein
- A–B · 696 Ų buried · 16 hydrogen bonds · protein-protein
- C–F · 689 Ų buried · 15 hydrogen bonds · protein-protein
- B–E · 639 Ų buried · 11 hydrogen bonds · protein-protein
- D–E · 629 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
- 7BFE · Circular permutant of ribosomal protein S6, P54-55 truncated, L21A mutant. · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5SLP8
- Elsewhere: RCSB PDB 7BFE · PDBe 7BFE · UniProt Q5SLP8
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.