Crystal structure of mure from E.COLI in complex with Z57299526

Structure

x-ray diffraction · 2 distinct chains.

Ligands and binding sites

• SYQ · (S)-N-(1-cyclopropylethyl)-6-methylpicolinamide · ligand · 2 copies · chains A, B
• T3Z · (R)-N-(1-cyclopropylethyl)-6-methylpicolinamide · ligand · 2 copies · chains A, B
• IPA · Isopropyl alcohol · additive · 4 copies · chains A, B
• CIT · Citric acid · additive · 2 copies · chains A, B
• DMS · Dimethyl sulfoxide · additive · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 7B61 · Crystal structure of MurE from E.coli in complex with Z57299526 · the same entry in another collection · chain A against A, TM-score 1.00
• P22188 · AlphaFold monomer V2.0 prediction for udp-N-acetylmuramoyl-L-alanyl… · a predicted model of the same protein · chain B against A, TM-score 0.80

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P22188
• Elsewhere: RCSB PDB 7B61 · PDBe 7B61 · UniProt P22188