MolNFT v1 · #173589 · protein

Cryoem structure of the human sodium proton exchanger NHA2

7B4L: “Cryoem structure of the human sodium proton exchanger NHA2”. Electron microscopy, 3 ligands (C14, POV, NA). MolNFT v1 #173589 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7B4L
Type: protein
Length: 886 residues
Chains: 2
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q86UD5
Ligands: C14, POV, NA

Structure

electron microscopy · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	—	protein	443	—	Q86UD5

Ligands and binding sites

C14 · Tetradecane · ligand · 6 copies · chains A, B
POV · (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate · ligand · 4 copies · chains A, B
NA · Sodium ion · metal · 2 copies · chains A, B
UND · Undecane · additive · 10 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7B4L · CryoEM structure of the human sodium proton exchanger NHA2 · the same entry in another collection · chain A against A, TM-score 1.00
Q86UD5 · AlphaFold monomer V2.0 prediction for SODIUM/HYDROGEN exchanger 9B2 (Q86UD5) · a predicted model of the same protein · chain A against A, TM-score 0.82

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q86UD5
Elsewhere: RCSB PDB 7B4L · PDBe 7B4L · UniProt Q86UD5

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