MolNFT v1 · #173382 · protein

Structure of WDR5:CS-VIP8 cocrystal after illumination in situ

7AXU · Wd repeat-containing protein 5: “Structure of WDR5:CS-VIP8 cocrystal after illumination in situ”. X-ray diffraction, 2 pockets (best druggability 0.76). MolNFT v1 #173382 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7AXU
Type: protein
Length: 313 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Wd repeat-containing protein 5
UniProt: P61964
Pockets: 2 · best druggability 0.76

Structure

x-ray diffraction · 1 distinct chain · 0% helix, 50% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Wd repeat-containing protein 5	protein	313	0% helix, 50% strand	P61964

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	702	0.76	0.81	69	empty
2	64	0.53	0.87	16	empty

Compared structures

7AXU · Structure of WDR5:CS-VIP8 cocrystal after illumination in situ · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P61964
Elsewhere: RCSB PDB 7AXU · PDBe 7AXU · UniProt P61964

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