MolNFT v1 · #173150 · protein
Crystal structure of small molecule inhibitor TM5484 bound to stabilized active plasminogen activator inhibitor-1 (pai-1-stab)
7AQF: “Crystal structure of small molecule inhibitor TM5484 bound to stabilized active plasminogen activator…”. X-ray diffraction, 1 ligand (RV2). MolNFT v1 #173150 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7AQF
- Type
- protein
- Length
- 736 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P05121
- Ligands
- RV2
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 370 | — | P05121 |
| B | — | protein | 366 | — | P05121 |
Ligands and binding sites
- RV2 · 5-Chloro-2-[[2-[3-(furan-3-yl)anilino]-2-oxoacetyl]amino]benzoic acid · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7AQF · Crystal Structure of Small Molecule Inhibitor TM5484 Bound to Stabilized Active… · the same entry in another collection · chain A against A, TM-score 1.00
- P05121 · AlphaFold monomer V2.0 prediction for plasminogen activator inhibitor 1 (P05121) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P05121
- Elsewhere: RCSB PDB 7AQF · PDBe 7AQF · UniProt P05121
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