MolNFT v1 · #173136 · protein
Crystal structure of human mature meprin beta in complex with the specific inhibitor mwt-S-270
7AQ1: “Crystal structure of human mature meprin beta in complex with the specific inhibitor mwt-S-270”. X-ray diffraction, 7 ligands (RUE, NAG, MAN). MolNFT v1 #173136 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7AQ1
- Type
- protein
- Length
- 1,066 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q16820
- Ligands
- RUE, NAG, MAN, BMA, CA, ZN, CL
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 533 | — | Q16820 |
Ligands and binding sites
- RUE · 3-[[(3-Carboxyphenyl)methyl-[2-(hydroxyamino)-2-oxoethyl]amino]methyl]benzoic acid · ligand · 2 copies · chains A, B
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 13 copies · chains A, B
- MAN · alpha-D-mannopyranose · sugar · 11 copies · chains A, B
- BMA · beta-D-mannopyranose · sugar · 2 copies · chains A, B
- CA · Calcium ion · metal · 4 copies · chains A, B
- ZN · Zinc ion · metal · 2 copies · chains A, B
- CL · Chloride ion · ion · 2 copies · chains A, B
- EDO · 1,2-ethanediol · additive · 5 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7AQ1 · Crystal structure of human mature meprin beta in complex with the specific inhibitor… · the same entry in another collection · chain A against A, TM-score 1.00
- Q16820 · AlphaFold monomer V2.0 prediction for meprin a subunit beta (Q16820) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q16820
- Elsewhere: RCSB PDB 7AQ1 · PDBe 7AQ1 · UniProt Q16820
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.