MolNFT v1 · #17300 · protein

Solution structure of neural cadherin prodomain

1OP4 · Neural-cadherin: “Solution structure of neural cadherin prodomain”. Solution nmr, 1 pocket (best druggability 0.35). MolNFT v1 #17300 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1OP4
Type: protein
Length: 136 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Neural-cadherin
UniProt: P15116
Pockets: 1 · best druggability 0.35

Structure

solution nmr · 1 distinct chain · 0% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Neural-cadherin	protein	136	0% helix, 30% strand	P15116

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	80	0.35	0.76	19	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

1OP4 · Solution Structure of Neural Cadherin Prodomain · the same entry in another collection · chain A against A, TM-score 1.00
P15116 · AlphaFold monomer V2.0 prediction for cadherin-2 (P15116) · a predicted model of the same protein · chain A against A, TM-score 0.60

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P15116
Elsewhere: RCSB PDB 1OP4 · PDBe 1OP4 · UniProt P15116

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