MolNFT v1 · #172548 · protein
Crystal structure of tetrameric human H215A-SAMHD1 (residues 109-626) with rp-dgtp-alphas (T8T) and mg
7A5Y: “Crystal structure of tetrameric human H215A-SAMHD1 (residues 109-626) with rp-dgtp-alphas (T8T) and mg”. X-ray diffraction, 3 ligands (T8T, MG, FE). MolNFT v1 #172548 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7A5Y
- Type
- protein
- Length
- 3,650 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9Y3Z3
- Ligands
- T8T, MG, FE
Structure
x-ray diffraction · 8 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 458 | — | Q9Y3Z3 |
| B | — | protein | 452 | — | Q9Y3Z3 |
| C | — | protein | 459 | — | Q9Y3Z3 |
| D | — | protein | 451 | — | Q9Y3Z3 |
| E | — | protein | 462 | — | Q9Y3Z3 |
| F | — | protein | 455 | — | Q9Y3Z3 |
| G | — | protein | 464 | — | Q9Y3Z3 |
| H | — | protein | 449 | — | Q9Y3Z3 |
Ligands and binding sites
- T8T · 2'-deoxyguanosine-5'-O-(1-thiotriphosphate) · ligand · 24 copies · chains A, B, C, D, E, F, H, G
- MG · Magnesium ion · metal · 24 copies · chains A, B, C, D, E, G, F, H
- FE · Fe (III) ion · metal · 8 copies · chains A, B, C, D, E, F, G, H
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7A5Y · Crystal structure of tetrameric human H215A-SAMHD1 (residues 109-626) with Rp-dGTP-alphaS… · the same entry in another collection · chain D against D, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y3Z3
- Elsewhere: RCSB PDB 7A5Y · PDBe 7A5Y · UniProt Q9Y3Z3
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