MolNFT v1 · #172242 · protein

Neisseria gonorrhoeae transaldolase

6ZWF: “Neisseria gonorrhoeae transaldolase”. X-ray diffraction, 1 ligand (OXY), 3 pockets (best druggability 0.57). MolNFT v1 #172242 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6ZWF
Type: protein
Length: 352 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transaldolase
EC: 2.2.1.2
UniProt: A0A1D3FXY0
Ligands: OXY
Pockets: 3 · best druggability 0.57

Structure

x-ray diffraction · 1 distinct chain · 58% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transaldolase (EC 2.2.1.2)	protein	352	58% helix, 12% strand	A0A1D3FXY0

Ligands and binding sites

OXY · Oxygen molecule · ion · chains A
BME · Beta-mercaptoethanol · additive · 4 copies · chains A
EDO · 1,2-ethanediol · additive · chains A
CIT · Citric acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	216	0.57	0.79	31	EDO, CIT
2	94	0.36	0.75	17	empty
3	67	0.30	0.74	15	empty

Modifications

Observed in the structure: 1 covalent (additive adduct).

Compared structures

6ZWF · Neisseria gonorrhoeae transaldolase · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A1D3FXY0
Elsewhere: RCSB PDB 6ZWF · PDBe 6ZWF · UniProt A0A1D3FXY0

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.