MolNFT v1 · #172207 · protein

Tfiis N-terminal domain (tnd) from human MED26

6ZV3 · Mediator of RNA polymerase II transcription subunit 26: “Tfiis N-terminal domain (tnd) from human MED26”. Solution nmr, 1 pocket (best druggability 0.29). MolNFT v1 #172207 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 6ZV3
Type: protein
Length: 90 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Mediator of RNA polymerase II transcription subunit 26
UniProt: O95402
Pockets: 1 · best druggability 0.29

Structure

solution nmr · 1 distinct chain · 64% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Mediator of RNA polymerase II transcription subunit 26	protein	90	64% helix, 2% strand	O95402

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	50	0.29	0.75	11	empty

Compared structures

6ZV3 · TFIIS N-terminal domain (TND) from human MED26 · the same entry in another collection · chain A against A, TM-score 1.00
O95402 · AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit… · a predicted model of the same protein · chain A against A, TM-score 0.89

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O95402
Elsewhere: RCSB PDB 6ZV3 · PDBe 6ZV3 · UniProt O95402

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