MolNFT v1 · #172205 · protein

Tfiis N-terminal domain (tnd) from human IWS1

6ZV1 · Protein IWS1 homolog: “Tfiis N-terminal domain (tnd) from human IWS1”. Solution nmr, 1 pocket (best druggability 0.27). MolNFT v1 #172205 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6ZV1
Type: protein
Length: 150 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein IWS1 homolog
UniProt: Q96ST2
Pockets: 1 · best druggability 0.27

Structure

solution nmr · 1 distinct chain · 65% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein IWS1 homolog	protein	150	65% helix, 0% strand	Q96ST2

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	64	0.27	0.72	13	empty

Compared structures

6ZV1 · TFIIS N-terminal domain (TND) from human IWS1 · the same entry in another collection · chain A against A, TM-score 1.00
Q96ST2 · AlphaFold monomer V2.0 prediction for protein IWS1 homolog (Q96ST2) · a predicted model of the same protein · chain A against A, TM-score 0.89

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q96ST2
Elsewhere: RCSB PDB 6ZV1 · PDBe 6ZV1 · UniProt Q96ST2

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