MolNFT v1 · #172124 · protein
Crystal structure of the bromodomain of human transcription activator BRG1 (SMARCA4) in complex with 2-(6-amino-5-(piperazin-1-yl) pyridazin-3-YL)PHENOL
6ZS2: “Crystal structure of the bromodomain of human transcription activator BRG1 (SMARCA4) in complex with…”. X-ray diffraction, 1 ligand (FX5). MolNFT v1 #172124 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6ZS2
- Type
- protein
- Length
- 242 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P51532
- Ligands
- FX5
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 121 | — | P51532 |
Ligands and binding sites
- FX5 · 2-(6-azanyl-5-piperazin-4-ium-1-yl-pyridazin-3-yl) phenol · ligand · 2 copies · chains A, B
- EDO · 1,2-ethanediol · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6ZS2 · Crystal Structure of the bromodomain of human transcription activator BRG1 (SMARCA4) in… · the same entry in another collection · chain A against A, TM-score 1.00
- P51532 · AlphaFold monomer V2.0 prediction for transcription activator BRG1 (P51532) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P51532
- Elsewhere: RCSB PDB 6ZS2 · PDBe 6ZS2 · UniProt P51532
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