MolNFT v1 · #172017 · protein
Fusidic acid binding to the TM7/TM8 groove of acrb-F380A T protomer
6ZOF: “Fusidic acid binding to the TM7/TM8 groove of acrb-F380A T protomer”. X-ray diffraction, 6 ligands (D10, DDQ, FUA). MolNFT v1 #172017 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6ZOF
- Type
- protein
- Length
- 3,420 residues
- Chains
- 5
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P31224
- Ligands
- D10, DDQ, FUA, R16, PTY, SO4
Structure
x-ray diffraction · 5 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 1042 | — | P31224 |
| B | — | protein | 1034 | — | P31224 |
| C | — | protein | 1035 | — | P31224 |
| D | — | protein | 155 | — | — |
| E | — | protein | 154 | — | — |
Ligands and binding sites
- D10 · Decane · ligand · chains B
- DDQ · Decylamine-N,N-dimethyl-N-oxide · ligand · chains A, B
- FUA · Fusidic acid · ligand · chains B
- R16 · Hexadecane · ligand · chains B, C
- PTY · Phosphatidylethanolamine · ligand · chains B, C
- SO4 · Sulfate ion · ion · 2 copies · chains A, C
- LMT · Dodecyl-beta-D-maltoside · additive · 5 copies · chains A, C, B
- GOL · Glycerol · additive · chains B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- P31224 · AlphaFold monomer V2.0 prediction for multidrug efflux pump subunit acrb (P31224) · a predicted model of the same protein · chain C against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P31224
- Elsewhere: RCSB PDB 6ZOF · PDBe 6ZOF · UniProt P31224
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