MolNFT v1 · #171989 · protein

Structure of the salmonella prgi needle filament attached to the basal body

6ZNH: “Structure of the salmonella prgi needle filament attached to the basal body”. Electron microscopy, 20 pockets (best druggability 0.60). MolNFT v1 #171989 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6ZNH
Type: protein
Length: 1,817 residues
Chains: 23
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Prgi
UniProt: P41784
Pockets: 20 · best druggability 0.60

Structure

electron microscopy · 1 distinct chain · 78% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W	Prgi	protein	79	78% helix, 0% strand	P41784

Pockets

20 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	327	0.60	0.78	56	empty
2	320	0.57	0.76	39	empty
3	310	0.56	0.76	40	empty
4	323	0.55	0.75	44	empty
5	311	0.55	0.75	40	empty

Interfaces

69 interfaces between chains.

M–S · 883 Å² buried · 7 hydrogen bonds · protein-protein
E–K · 880 Å² buried · 7 hydrogen bonds · protein-protein
F–M · 880 Å² buried · 7 hydrogen bonds · protein-protein
C–I · 880 Å² buried · 5 hydrogen bonds · protein-protein
Q–W · 879 Å² buried · 5 hydrogen bonds · protein-protein

Compared structures

6ZNH · Structure of the Salmonella PrgI needle filament attached to the basal body · the same entry in another collection · chain W against W, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P41784
Elsewhere: RCSB PDB 6ZNH · PDBe 6ZNH · UniProt P41784

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