MolNFT v1 · #171807 · protein
Crystal structure of fatty acid photodecarboxylase in the dark state determined by serial femtosecond crystallography at room temperature
6ZH7 · Fatty acid photodecarboxylase, chloroplastic: “Crystal structure of fatty acid photodecarboxylase in the dark state determined by serial femtosecond…”. X-ray diffraction, 2 ligands (STE, FAD), 10 pockets (best druggability 0.88).…
- PDB
- 6ZH7
- Type
- protein
- Length
- 1,125 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fatty acid photodecarboxylase, chloroplastic
- EC
- 4.1.1.106
- UniProt
- A0A248QE08
- Ligands
- STE, FAD
- Pockets
- 10 · best druggability 0.88
Structure
x-ray diffraction · 2 distinct chains · 30% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fatty acid photodecarboxylase, chloroplastic (EC 4.1.1.106) | protein | 563 | 29% helix, 22% strand | A0A248QE08 |
| B | Fatty acid photodecarboxylase, chloroplastic (EC 4.1.1.106) | protein | 562 | 30% helix, 22% strand | A0A248QE08 |
Ligands and binding sites
- STE · Stearic acid · ligand · 4 copies · chains A, B
- FAD · Flavin-adenine dinucleotide · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 556 | 0.88 | 0.94 | 97 | FAD, STE |
| 2 | 558 | 0.87 | 0.93 | 101 | FAD, STE |
| 3 | 386 | 0.64 | 0.79 | 45 | empty |
| 4 | 90 | 0.56 | 0.85 | 17 | STE |
| 5 | 96 | 0.55 | 0.84 | 17 | STE |
Interfaces
1 interface between chains.
- A–B · 338 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 6ZH7 · Crystal structure of fatty acid photodecarboxylase in the dark state determined by serial… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A248QE08
- Elsewhere: RCSB PDB 6ZH7 · PDBe 6ZH7 · UniProt A0A248QE08
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