MolNFT v1 · #171702 · protein + RNA

Structure of telomerase from candida albicans in complexe with twj fragment of telomeric RNA

6ZDQ · Telomerase reverse transcriptase: “Structure of telomerase from candida albicans in complexe with twj fragment of telomeric RNA”. X-ray diffraction, 19 pockets (best druggability 0.66). MolNFT v1 #171702 on GenesisL1: 3D structure…

PDB: 6ZDQ
Type: protein + RNA
Length: 742 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Telomerase reverse transcriptase; RNA
EC: 2.7.7.49
UniProt: A0A1D8PEA0
Pockets: 19 · best druggability 0.66

Structure

x-ray diffraction · 2 distinct chains · 49% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Telomerase reverse transcriptase (EC 2.7.7.49)	protein	677	49% helix, 12% strand	A0A1D8PEA0
C	RNA	rna	65	—	—

Pockets

19 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	148	0.66	0.88	26	empty
2	304	0.62	0.80	29	empty
3	191	0.60	0.82	20	empty
4	209	0.57	0.80	23	empty
5	208	0.54	0.77	29	empty

Interfaces

1 interface between chains.

A–C · 1980 Å² buried · 43 hydrogen bonds · protein-nucleic

Compared structures

6ZDQ · Structure of telomerase from Candida albicans in complexe with TWJ fragment of telomeric… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A1D8PEA0
Elsewhere: RCSB PDB 6ZDQ · PDBe 6ZDQ · UniProt A0A1D8PEA0

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