Research workbench
Structure of telomerase from candida albicans in complexe with twj fragment of telomeric RNA
Analyse Structure of telomerase from candida albicans in complexe with twj fragment of… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6ZDQ
- Type
- protein + RNA
- Length
- 742 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Telomerase reverse transcriptase; RNA
- EC
- 2.7.7.49
- UniProt
- A0A1D8PEA0
- Pockets
- 19 · best druggability 0.66
Structure
x-ray diffraction · 2 distinct chains · 49% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Telomerase reverse transcriptase (EC 2.7.7.49) | protein | 677 | 49% helix, 12% strand | A0A1D8PEA0 |
| C | RNA | rna | 65 | — | — |
Pockets
19 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 148 | 0.66 | 0.88 | 26 | empty |
| 2 | 304 | 0.62 | 0.80 | 29 | empty |
| 3 | 191 | 0.60 | 0.82 | 20 | empty |
| 4 | 209 | 0.57 | 0.80 | 23 | empty |
| 5 | 208 | 0.54 | 0.77 | 29 | empty |
Interfaces
1 interface between chains.
- A–C · 1980 Ų buried · 43 hydrogen bonds · protein-nucleic
Compared structures
- 6ZDQ · Structure of telomerase from Candida albicans in complexe with TWJ fragment of telomeric… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A1D8PEA0
- Elsewhere: RCSB PDB 6ZDQ · PDBe 6ZDQ · UniProt A0A1D8PEA0
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.