Variant surface glycoprotein vsgsur, I3C ("magic triangle") derivative used for phasing of the structure and subsequently as a model for molecular replacement of native, mutants, and drug soaks.

Structure

x-ray diffraction · 1 distinct chain · 49% helix, 15% strand (DSSP).

Ligands and binding sites

• I3C · 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid · ligand · chains A
• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains A
• MAN · alpha-D-mannopyranose · sugar · 2 copies · chains A
• BMA · beta-D-mannopyranose · sugar

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Modifications

Observed in the structure: 3 disulfide, 1 glycan (disulfide, N-glycosylation).

Compared structures

• 6Z79 · Variant Surface Glycoprotein VSGsur, I3C ("Magic Triangle") derivative used for phasing… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt A0A291L8F4
• Elsewhere: RCSB PDB 6Z79 · PDBe 6Z79 · UniProt A0A291L8F4