MolNFT v1 · #171448 · protein
Crystal structure of haspin (GSG2) in complex with macrocycle ODS2004070
6Z5C: “Crystal structure of haspin (GSG2) in complex with macrocycle ODS2004070”. X-ray diffraction, 3 ligands (PQ5, NA, PO4). MolNFT v1 #171448 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6Z5C
- Type
- protein
- Length
- 329 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q8TF76
- Ligands
- PQ5, NA, PO4
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 329 | — | Q8TF76 |
Ligands and binding sites
- PQ5 · 7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12, 6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene-5-carboxylic acid · ligand · chains A
- NA · Sodium ion · metal · chains A
- PO4 · Phosphate ion · ion · chains A
- DMS · Dimethyl sulfoxide · additive · chains A
- SIN · Succinic acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6Z5C · Crystal structure of haspin (GSG2) in complex with macrocycle ODS2004070 · the same entry in another collection · chain A against A, TM-score 1.00
- Q8TF76 · AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase haspin (Q8TF76) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8TF76
- Elsewhere: RCSB PDB 6Z5C · PDBe 6Z5C · UniProt Q8TF76
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