Ligand · PQ5
PQ5 · 7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12, 6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene-5-carboxylic acid
PQ5, 7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12, 6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene-5-carboxylic acid (C17 H16 N4 O4, 340.3 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (3 PDB entries). Every…
- Component
- PQ5
- Formula
- C17 H16 N4 O4
- Class
- ligand
- Structures
- 5
- PDB entries
- 3
Binding sites
PQ5 in 5 structures; the first of them:
- 6Z4Z · Crystal structure of CLK1 in complex with macrocycle ODS2004070 · PQ5 A505 · binds LEU167, GLY168, VAL175, ALA189, LYS191, GLU206, VAL225, PHE241 and 9 more
- 6Z55 · Crystal structure of CLK3 in complex with macrocycle ODS2004070 · PQ5 A519 · binds LEU162, VAL170, ALA184, LYS186, GLU201, VAL220, PHE236, GLU237 and 7 more
- 6Z4Z · Crystal structure of CLK1 in complex with macrocycle ODS2004070 · PQ5 A505 · binds LEU167, GLY168, VAL175, ALA189, LYS191, GLU206, PHE241, GLU242 and 8 more
- 6Z55 · Crystal structure of CLK3 in complex with macrocycle ODS2004070 · PQ5 A519 · binds LEU162, VAL170, ALA184, LYS186, VAL220, PHE236, GLU237, LEU238 and 4 more
- 6Z5C · Crystal structure of haspin (GSG2) in complex with macrocycle ODS2004070 · PQ5 A805 · binds ILE490, PHE495, VAL498, ALA509, LYS511, PHE605, GLU606, GLY608 and 4 more
Residues it binds most
LEU 11, GLU 11, VAL 11, ALA 11, PHE 11, GLY 9, ASP 11, LYS 11, ASN 5, ILE 1 (residue and the binding sites it lines).
Found with
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