MolNFT v1 · #171371 · protein
The structure of the dimeric HDAC1/MIDEAS/DNTTIP1 midac deacetylase complex
6Z2J: “The structure of the dimeric HDAC1/MIDEAS/DNTTIP1 midac deacetylase complex”. Electron microscopy, 3 ligands (IHP, K, ZN). MolNFT v1 #171371 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6Z2J
- Type
- protein
- Length
- 1,185 residues
- Chains
- 6
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q13547, Q9H147, Q6PJG2
- Ligands
- IHP, K, ZN
Structure
electron microscopy · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| C | — | protein | 369 | — | Q13547 |
| E | — | protein | 368 | — | Q13547 |
| A, B | — | protein | 69 | — | Q9H147 |
| F, D | — | protein | 155 | — | Q6PJG2 |
Ligands and binding sites
- IHP · Inositol hexakisphosphate · ligand · 2 copies · chains C, D, E, F
- K · Potassium ion · metal · 4 copies · chains C, E
- ZN · Zinc ion · metal · 2 copies · chains C, E
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6Z2J · The structure of the dimeric HDAC1/MIDEAS/DNTTIP1 MiDAC deacetylase complex · the same entry in another collection · chain D against D, TM-score 1.00
- Q13547 · AlphaFold monomer V2.0 prediction for histone deacetylase 1 (Q13547) · a predicted model of the same protein · chain C against A, TM-score 0.96
- Q9H147 · AlphaFold monomer V2.0 prediction for deoxynucleotidyltransferase terminal-interacting… · a predicted model of the same protein · chain A against A, TM-score 0.92
- Q6PJG2 · AlphaFold monomer V2.0 prediction for mitotic deacetylase-associated sant domain protein… · a predicted model of the same protein · chain F against A, TM-score 0.78
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13547
- Every structure of UniProt Q9H147
- Every structure of UniProt Q6PJG2
- Elsewhere: RCSB PDB 6Z2J · PDBe 6Z2J · UniProt Q13547 · UniProt Q9H147 · UniProt Q6PJG2
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