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MolNFT v1 · #171259 · protein

Structure of mycobacterium smegmatis held protein in complex with RNA polymerase core - state II, primary channel engaged and active site interfering

6YYS: “Structure of mycobacterium smegmatis held protein in complex with RNA polymerase core - state II, primary…”. Electron microscopy, 2 ligands (ZN, MG). MolNFT v1 #171259 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6YYS
Type
protein
Length
3,597 residues
Chains
6
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
A0QSL8, P60281, A0QS66, A0QWT1, A0QUE0
Ligands
ZN, MG

Structure

electron microscopy · 6 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein224—A0QSL8
B—protein233—A0QSL8
C—protein1089—P60281
D—protein1278—A0QS66
E—protein83—A0QWT1
H—protein690—A0QUE0

Ligands and binding sites

  • ZN · Zinc ion · metal · 2 copies · chains D
  • MG · Magnesium ion · metal · chains D, H

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6YYS · Structure of Mycobacterium smegmatis HelD protein in complex with RNA polymerase core… · the same entry in another collection · chain H against H, TM-score 1.00
  • P60281 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta (P60281) · a predicted model of the same protein · chain C against A, TM-score 0.98
  • A0QSL8 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (A0QSL8) · a predicted model of the same protein · chain A against A, TM-score 0.96
  • A0QWT1 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit omega (A0QWT1) · a predicted model of the same protein · chain E against A, TM-score 0.92
  • A0QS66 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta' (A0QS66) · a predicted model of the same protein · chain D against A, TM-score 0.79

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