MolNFT v1 · #170888 · protein

Crystal structure of bay-297 with PIP4K2A

6YM4: “Crystal structure of bay-297 with PIP4K2A”. X-ray diffraction, 1 ligand (P4Z). MolNFT v1 #170888 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6YM4
Type: protein
Length: 634 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P48426
Ligands: P4Z

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	322	—	P48426
B	—	protein	312	—	P48426

Ligands and binding sites

P4Z · (2~{R})-2-[[2-[4-(3-chloranyl-2-fluoranyl-phenyl) phenyl]-3-cyano-1,7-naphthyridin-4-yl]amino]butanamide · ligand · 2 copies · chains A, B
GOL · Glycerol · additive · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6YM4 · Crystal structure of BAY-297 with PIP4K2A · the same entry in another collection · chain A against A, TM-score 1.00
P48426 · AlphaFold monomer V2.0 prediction for phosphatidylinositol 5-phosphate 4-kinase type-2… · a predicted model of the same protein · chain B against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P48426
Elsewhere: RCSB PDB 6YM4 · PDBe 6YM4 · UniProt P48426

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