GL1X · GenesisL1 explorer

MolNFT v1 · #170883 · protein

Translation initiation factor 4E in complex with 4-cl-BN7GPPPG mRNA 5' cap analog

6YLV: “Translation initiation factor 4E in complex with 4-cl-BN7GPPPG mRNA 5' cap analog”. X-ray diffraction, 1 ligand (OYW). MolNFT v1 #170883 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6YLV
Type
protein
Length
725 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
P63073
Ligands
OYW

Structure

x-ray diffraction · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein183—P63073
B—protein185—P63073
C—protein179—P63073
D—protein178—P63073

Ligands and binding sites

  • OYW · 4-Cl-Bn7GpppG mRNA 5' cap analog · ligand · 4 copies · chains A, B, C, D
  • GOL · Glycerol · additive · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6YLV · Translation initiation factor 4E in complex with 4-Cl-Bn7GpppG mRNA 5' cap analog · the same entry in another collection · chain D against D, TM-score 1.00
  • P63073 · AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 4E (P63073) · a predicted model of the same protein · chain C against A, TM-score 0.98

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