MolNFT v1 · #170622 · protein

X-ray structure of furin in complex with the canavanine-based inhibitor 4-guanidinomethyl-phenylacetyl-arg-tle-canavanine-amba

6YD7: “X-ray structure of furin in complex with the canavanine-based inhibitor…”. X-ray diffraction, 6 ligands (2UE, 00S, CA). MolNFT v1 #170622 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6YD7
Type: protein
Length: 476 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P09958
Ligands: 2UE, 00S, CA, NA, PO4, CL

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	476	—	P09958

Ligands and binding sites

2UE · 1-[4-(2-oxoethyl)benzyl]guanidine · ligand · chains A
00S · 4-(aminomethyl)benzenecarboximidamide · ligand · chains A
CA · Calcium ion · metal · 3 copies · chains A
NA · Sodium ion · metal · 3 copies · chains A
PO4 · Phosphate ion · ion · 2 copies · chains A
CL · Chloride ion · ion · chains A
DMS · Dimethyl sulfoxide · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6YD7 · X-ray structure of furin in complex with the canavanine-based inhibitor… · the same entry in another collection · chain A against A, TM-score 0.99
P09958 · AlphaFold monomer V2.0 prediction for furin (P09958) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P09958
Elsewhere: RCSB PDB 6YD7 · PDBe 6YD7 · UniProt P09958

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.