MolNFT v1 · #170487 · protein

CA2+-free calmodulin mutant N53I

6Y95: “CA2+-free calmodulin mutant N53I”. Solution nmr, 2 pockets (best druggability 0.61). MolNFT v1 #170487 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6Y95
Type: protein
Length: 148 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Calmodulin
UniProt: P0DP23
Pockets: 2 · best druggability 0.61

Structure

solution nmr · 1 distinct chain · 53% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Calmodulin	protein	148	53% helix, 9% strand	P0DP23

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	525	0.61	0.74	41	empty
2	63	0.28	0.73	13	empty

Compared structures

6Y95 · Ca2+-free Calmodulin mutant N53I · the same entry in another collection · chain A against A, TM-score 1.00
P0DP23 · AlphaFold monomer V2.0 prediction for calmodulin-1 (P0DP23) · a predicted model of the same protein · chain A against A, TM-score 0.38

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0DP23
Elsewhere: RCSB PDB 6Y95 · PDBe 6Y95 · UniProt P0DP23

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