MolNFT v1 · #170436 · protein

Structure of the BRD9 bromodomain and compound 2

6Y7I: “Structure of the BRD9 bromodomain and compound 2”. X-ray diffraction, 1 ligand (OF8). MolNFT v1 #170436 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6Y7I
Type: protein
Length: 228 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q9H8M2
Ligands: OF8

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	—	protein	114	—	Q9H8M2

Ligands and binding sites

OF8 · 1-(8-pyridin-2-ylpyrrolo[1,2-a]pyrimidin-6-yl)ethanone · ligand · 2 copies · chains A, B
EDO · 1,2-ethanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6Y7I · Structure of the BRD9 bromodomain and compound 2 · the same entry in another collection · chain A against A, TM-score 1.00
Q9H8M2 · AlphaFold monomer V2.0 prediction for bromodomain-containing protein 9 (Q9H8M2) · a predicted model of the same protein · chain B against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9H8M2
Elsewhere: RCSB PDB 6Y7I · PDBe 6Y7I · UniProt Q9H8M2

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