MolNFT v1 · #170126 · protein

Crystal structure of human deoxyhypusine synthase in apo form

6XXH: “Crystal structure of human deoxyhypusine synthase in apo form”. X-ray diffraction, 1 ligand (OXM). MolNFT v1 #170126 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6XXH
Type: protein
Length: 667 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P49366
Ligands: OXM

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	331	—	P49366
B	—	protein	336	—	P49366

Ligands and binding sites

OXM · Oxamic acid · ligand
BME · Beta-mercaptoethanol · additive · chains A
MRD · (4R)-2-methylpentane-2,4-diol · additive · chains B
ACT · Acetate ion · additive · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6XXH · Crystal Structure of Human Deoxyhypusine Synthase in apo form · the same entry in another collection · chain A against A, TM-score 1.00
P49366 · AlphaFold monomer V2.0 prediction for deoxyhypusine synthase (P49366) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P49366
Elsewhere: RCSB PDB 6XXH · PDBe 6XXH · UniProt P49366

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