MolNFT v1 · #170071 · protein
Crystal structure of the kdr (VEGFR2) kinase domain in complex with a type-II inhibitor bearing an acrylamide
6XVK: “Crystal structure of the kdr (VEGFR2) kinase domain in complex with a type-II inhibitor bearing an acrylamide”. X-ray diffraction, 1 ligand (O3E). MolNFT v1 #170071 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6XVK
- Type
- protein
- Length
- 298 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P35968
- Ligands
- O3E
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 298 | — | P35968 |
Ligands and binding sites
- O3E · ~{N}-(4,4-dimethyl-2-prop-1-ynyl-3,1-benzoxazin-6-yl)-2-[3-methoxy-5-(7-methoxyquinolin-4-yl)oxy-pyridin-2-yl]ethanamide · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6XVK · Crystal structure of the KDR (VEGFR2) kinase domain in complex with a type-II inhibitor… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P35968
- Elsewhere: RCSB PDB 6XVK · PDBe 6XVK · UniProt P35968
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