MolNFT v1 · #170020 · protein
Crystal structure of tetrameric human H215A-SAMHD1 (residues 109-626) with GTP, dampnpp and mg
6XU1: “Crystal structure of tetrameric human H215A-SAMHD1 (residues 109-626) with GTP, dampnpp and mg”. X-ray diffraction, 4 ligands (DZ4, GTP, MG). MolNFT v1 #170020 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6XU1
- Type
- protein
- Length
- 3,816 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9Y3Z3
- Ligands
- DZ4, GTP, MG, FE
Structure
x-ray diffraction · 7 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 480 | — | Q9Y3Z3 |
| B | — | protein | 479 | — | Q9Y3Z3 |
| C | — | protein | 478 | — | Q9Y3Z3 |
| D, H | — | protein | 478 | — | Q9Y3Z3 |
| E | — | protein | 464 | — | Q9Y3Z3 |
| F | — | protein | 480 | — | Q9Y3Z3 |
| G | — | protein | 479 | — | Q9Y3Z3 |
Ligands and binding sites
- DZ4 · 2'-deoxy-5'-O-[(R)-hydroxy{[(r)-hydroxy(phosphonooxy) phosphoryl]amino}phosphoryl]adenosine · ligand · 16 copies · chains A, C, D, B, E, G, H, F
- GTP · Guanosine-5'-triphosphate · ligand · 8 copies · chains A, B, C, D, E, F, G, H
- MG · Magnesium ion · metal · 25 copies · chains A, B, C, D, E, F, G, H
- FE · Fe (III) ion · metal · 8 copies · chains A, B, C, D, E, F, G, H
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6XU1 · Crystal structure of tetrameric human H215A-SAMHD1 (residues 109-626) with GTP, dAMPNPP… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y3Z3
- Elsewhere: RCSB PDB 6XU1 · PDBe 6XU1 · UniProt Q9Y3Z3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.