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MolNFT v1 · #169490 · protein

Crystal structure of mbp-TREM2 ig domain fusion with fragment, 2-((4- BROMOPHENYL)AMINO)ETHAN-1-ol

6XDS: “Crystal structure of mbp-TREM2 ig domain fusion with fragment, 2-((4- BROMOPHENYL)AMINO)ETHAN-1-ol”. X-ray diffraction, 2 ligands (V5S, GLC). MolNFT v1 #169490 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6XDS
Type
protein
Length
485 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt
A0A0F8NYV9, Q9NZC2
Ligands
V5S, GLC

Structure

x-ray diffraction · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein485—A0A0F8NYV9, Q9NZC2

Ligands and binding sites

  • V5S · 2-[(4-bromophenyl)amino]ethan-1-ol · ligand · chains A
  • GLC · alpha-D-glucopyranose · sugar · 3 copies · chains A
  • DMS · Dimethyl sulfoxide · additive · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6XDS · Crystal structure of MBP-TREM2 Ig domain fusion with fragment… · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9NZC2 · AlphaFold monomer V2.0 prediction for triggering receptor expressed on myeloid cells 2… · a predicted model of the same protein · chain A against A, TM-score 0.25

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