MolNFT v1 · #169453 · protein
Histone-lysine N-methyltransferase NSD2-PWWP1 with compound UNC6934
6XCG: “Histone-lysine N-methyltransferase NSD2-PWWP1 with compound UNC6934”. X-ray diffraction, 2 ligands (V01, UNX). MolNFT v1 #169453 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6XCG
- Type
- protein
- Length
- 397 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O96028
- Ligands
- V01, UNX
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 133 | — | O96028 |
| C | — | protein | 131 | — | O96028 |
Ligands and binding sites
- V01 · N-cyclopropyl-3-oxo-N-({4-[(pyrimidin-4-yl) carbamoyl]phenyl}methyl)-3,4-dihydro-2H-1,4-benzoxazine-7-carboxamide · ligand · 3 copies · chains A, B, C
- UNX · Unknown atom or ion · ion · 6 copies · chains B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6XCG · Histone-lysine N-methyltransferase NSD2-PWWP1 with compound UNC6934 · the same entry in another collection · chain A against A, TM-score 1.00
- O96028 · AlphaFold monomer V2.0 prediction for histone-lysine N-methyltransferase NSD2 (O96028) · a predicted model of the same protein · chain C against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O96028
- Elsewhere: RCSB PDB 6XCG · PDBe 6XCG · UniProt O96028
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