MolNFT v1 · #169357 · protein

Pseudomonas aeruginosa murc with AZ8074

6X9F: “Pseudomonas aeruginosa murc with AZ8074”. X-ray diffraction, 2 ligands (UXP, CL). MolNFT v1 #169357 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6X9F
Type: protein
Length: 2,434 residues
Chains: 8
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q9HW02
Ligands: UXP, CL

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, D, E, G, H	—	protein	304	—	Q9HW02
C, F	—	protein	305	—	Q9HW02

Ligands and binding sites

UXP · [(2R)-1-{4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-2H-pyrazolo[3,4-d]pyrimidin-6-yl}piperidin-2-yl]methanol · ligand · 8 copies · chains A, B, C, D, E, F, G, H
CL · Chloride ion · ion · 5 copies · chains D, E, F, H, G
EDO · 1,2-ethanediol · additive · 32 copies · chains A, G, B, E, C, D, F, H
DMS · Dimethyl sulfoxide · additive · 13 copies · chains A, B, E, D, F, G, H

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6X9F · Pseudomonas aeruginosa MurC with AZ8074 · the same entry in another collection · chain H against H, TM-score 1.00
Q9HW02 · AlphaFold monomer V2.0 prediction for udp-N-acetylmuramate--L-alanine ligase (Q9HW02) · a predicted model of the same protein · chain C against A, TM-score 0.87

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9HW02
Elsewhere: RCSB PDB 6X9F · PDBe 6X9F · UniProt Q9HW02

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.