GL1X · GenesisL1 explorer

Ligand · UXP

UXP · [(2R)-1-{4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-2H-pyrazolo[3,4-d]pyrimidin-6-yl}piperidin-2-yl]methanol

UXP, [(2R)-1-{4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-2H-pyrazolo[3,4-d]pyrimidin-6-yl}piperidin-2-yl]methanol (C17 H22 N8 O, 354.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with…

Component
UXP
Formula
C17 H22 N8 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

UXP in 2 structures; the first of them:

  • 6X9F · Pseudomonas aeruginosa MurC with AZ8074 · UXP A501 · binds HIS117, GLY118, THR121, THR122, THR182, ASN183, CYS219, ASP222 and 5 more
  • 6X9F · Pseudomonas aeruginosa murc with AZ8074 · UXP A501 · binds HIS117, GLY118, THR182, ASN183, CYS219, ASP222, TYR239, HIS281 and 2 more

Residues it binds most

ASN 16, THR 16, HIS 16, CYS 16, GLY 16, LEU 16, TYR 16, ASP 7 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion
  • DMS · Dimethyl sulfoxide
  • EDO · 1,2-ethanediol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.