MolNFT v1 · #169074 · protein
ASH1L set domain in complex with as-85
6WZW: “ASH1L set domain in complex with as-85”. X-ray diffraction, 2 ligands (UG7, ZN). MolNFT v1 #169074 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6WZW
- Type
- protein
- Length
- 222 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q9NR48
- Ligands
- UG7, ZN
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 222 | — | Q9NR48 |
Ligands and binding sites
- UG7 · N-{[3-(3-carbamothioylphenyl)-1-{1-[(trifluoromethyl) sulfonyl]piperidin-4-yl}-1H-indol-6-yl]methyl}azetidine-3-carboxamide · ligand · chains A
- ZN · Zinc ion · metal · 3 copies · chains A
- EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6WZW · Ash1L SET domain in complex with AS-85 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9NR48
- Elsewhere: RCSB PDB 6WZW · PDBe 6WZW · UniProt Q9NR48
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