Human vkor with brodifacoum

Structure

x-ray diffraction · 2 distinct chains.

Ligands and binding sites

• CRO · {2-[(1R,2R)-1-amino-2-hydroxypropyl]-4-(4-hydroxybenzylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl}acetic acid · ligand · 2 copies · chains A, B
• UA7 · Brodifacoum · ligand · 2 copies · chains A, B
• OLC · (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 6WVH · Human VKOR with Brodifacoum · the same entry in another collection · chain A against A, TM-score 1.00
• Q9BQB6 · AlphaFold monomer V2.0 prediction for vitamin K epoxide reductase complex subunit 1… · a predicted model of the same protein · chain A against A, TM-score 0.42

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt A0A059PIQ0
• Every structure of UniProt Q9BQB6
• Elsewhere: RCSB PDB 6WVH · PDBe 6WVH · UniProt A0A059PIQ0 · UniProt Q9BQB6