MolNFT v1 · #168886 · protein
Human calcium and integrin binding protein 3 E150Q K151H
6WU7 · Calcium and integrin-binding family member 3: “Human calcium and integrin binding protein 3 E150Q K151H”. X-ray diffraction, 1 ligand (CA), 1 pocket (best druggability 0.80). MolNFT v1 #168886 on GenesisL1: 3D structure, binding…
- PDB
- 6WU7
- Type
- protein
- Length
- 364 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Calcium and integrin-binding family member 3
- UniProt
- Q96Q77
- Ligands
- CA
- Pockets
- 1 · best druggability 0.80
Structure
x-ray diffraction · 2 distinct chains · 54% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Calcium and integrin-binding family member 3 | protein | 181 | 54% helix, 2% strand | Q96Q77 |
| B | Calcium and integrin-binding family member 3 | protein | 183 | 55% helix, 2% strand | Q96Q77 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 870 | 0.80 | 0.82 | 82 | CA |
Interfaces
1 interface between chains.
- A–B · 1944 Ų buried · 18 hydrogen bonds · protein-protein
Compared structures
- 6WU7 · Human Calcium and Integrin Binding Protein 3 E150Q K151H · the same entry in another collection · chain A against A, TM-score 1.00
- Q96Q77 · AlphaFold monomer V2.0 prediction for calcium and integrin-binding family member 3… · a predicted model of the same protein · chain A against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96Q77
- Elsewhere: RCSB PDB 6WU7 · PDBe 6WU7 · UniProt Q96Q77
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