MolNFT v1 · #16888 · protein

Structure native of the D405N mutant of the cellobiohydrolase CEL6A from humicola insolens at 1.5 ångström resolution

1OC6 · Cellobiohydrolase II: “Structure native of the D405N mutant of the cellobiohydrolase CEL6A from humicola insolens at 1.5 ångström…”. X-ray diffraction, 2 ligands (NAG, CA), 1 pocket (best druggability 0.76). MolNFT v1 #16888 on…

PDB: 1OC6
Type: protein
Length: 364 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cellobiohydrolase II
EC: 3.2.1.91
Ligands: NAG, CA
Pockets: 1 · best druggability 0.76

Structure

x-ray diffraction · 1 distinct chain · 38% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cellobiohydrolase II (EC 3.2.1.91)	protein	364	38% helix, 13% strand	—

Ligands and binding sites

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
CA · Calcium ion · metal · chains A
GOL · Glycerol · additive · 7 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	518	0.76	0.84	55	GOL

Modifications

Observed in the structure: 2 disulfide, 1 glycan (disulfide, N-glycosylation).

Compared structures

1OC6 · structure native of the D405N mutant of the CELLOBIOHYDROLASE CEL6A FROM HUMICOLA… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 1OC6 · PDBe 1OC6

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