MolNFT v1 · #168875 · protein
Structure of laindy crystallized in the presence of alpha- ketoglutarate and malate
6WTW · Dass family sodium-coupled anion symporter: “Structure of laindy crystallized in the presence of alpha- ketoglutarate and malate”. X-ray diffraction, 10 pockets (best druggability 0.77). MolNFT v1 #168875 on GenesisL1: 3D structure…
- PDB
- 6WTW
- Type
- protein
- Length
- 978 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Dass family sodium-coupled anion symporter
- UniProt
- A0A3A9Y7Q2
- Pockets
- 10 · best druggability 0.77
Structure
x-ray diffraction · 1 distinct chain · 73% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Dass family sodium-coupled anion symporter | protein | 489 | 73% helix, 1% strand | A0A3A9Y7Q2 |
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1099 | 0.77 | 0.79 | 136 | empty |
| 2 | 108 | 0.61 | 0.86 | 23 | empty |
| 3 | 343 | 0.60 | 0.77 | 34 | empty |
| 4 | 182 | 0.59 | 0.81 | 19 | empty |
| 5 | 373 | 0.57 | 0.75 | 40 | empty |
Interfaces
1 interface between chains.
- A–B · 2714 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 6WTW · Structure of LaINDY crystallized in the presence of alpha-ketoglutarate and malate · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A3A9Y7Q2
- Elsewhere: RCSB PDB 6WTW · PDBe 6WTW · UniProt A0A3A9Y7Q2
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