MolNFT v1 · #168851 · protein

Structure of a sting-associated cdne C-di-gmp synthase from flavobacteriaceae sp.

6WT8: “Structure of a sting-associated cdne C-di-gmp synthase from flavobacteriaceae sp.”. X-ray diffraction, 4 pockets (best druggability 0.62). MolNFT v1 #168851 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6WT8
Type: protein
Length: 356 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sting-associated cdne C-di-gmp synthase
Pockets: 4 · best druggability 0.62

Structure

x-ray diffraction · 1 distinct chain · 56% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sting-associated cdne C-di-gmp synthase	protein	356	56% helix, 13% strand	—

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	406	0.62	0.77	40	empty
2	192	0.48	0.76	26	empty
3	72	0.40	0.79	15	empty
4	53	0.33	0.77	14	empty

Modifications

Observed in the structure: 7 modified (engineered).

Compared structures

6WT8 · Structure of a STING-associated CdnE c-di-GMP synthase from Flavobacteriaceae sp. · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 6WT8 · PDBe 6WT8

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