MolNFT v1 · #168827 · protein

Crystal structure of the cannabinoid receptor 1 interacting protein 1A (CRIP1A)

6WSK · ENDOLYSIN,CB1 cannabinoid receptor-interacting protein 1…: “Crystal structure of the cannabinoid receptor 1 interacting protein 1A (CRIP1A)”. X-ray diffraction, 3 pockets (best druggability 0.60). MolNFT v1 #168827 on GenesisL1: 3D…

PDB: 6WSK
Type: protein
Length: 287 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: ENDOLYSIN,CB1 cannabinoid receptor-interacting protein 1 fusion
EC: 3.2.1.17
UniProt: P00720, Q5M7A7
Pockets: 3 · best druggability 0.60

Structure

x-ray diffraction · 1 distinct chain · 34% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	ENDOLYSIN,CB1 cannabinoid receptor-interacting protein 1 fusion (EC 3.2.1.17)	protein	287	34% helix, 33% strand	P00720, Q5M7A7

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	285	0.60	0.79	31	empty
2	81	0.35	0.75	19	empty
3	68	0.32	0.75	12	empty

Compared structures

6WSK · Crystal Structure of the Cannabinoid Receptor 1 Interacting Protein 1a (CRIP1a) · the same entry in another collection · chain A against A, TM-score 1.00
Q5M7A7 · AlphaFold monomer V2.0 prediction for CB1 cannabinoid receptor- interacting protein 1… · a predicted model of the same protein · chain A against A, TM-score 0.50

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00720
Every structure of UniProt Q5M7A7
Elsewhere: RCSB PDB 6WSK · PDBe 6WSK · UniProt P00720 · UniProt Q5M7A7

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