MolNFT v1 · #168737 · protein

Human nik in complex with ligand compound X

6WPP: “Human nik in complex with ligand compound X”. X-ray diffraction, 1 ligand (PZ4). MolNFT v1 #168737 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6WPP
Type: protein
Length: 627 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q99558
Ligands: PZ4

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	312	—	Q99558
B	—	protein	315	—	Q99558

Ligands and binding sites

PZ4 · 5-fluoro-N-methyl-2-(7H-pyrrolo[2,3-d]pyrimidin-5-yl) pyrimidin-4-amine · ligand · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6WPP · Human nik in complex with ligand compound X · the same entry in another collection · chain A against A, TM-score 1.00
Q99558 · AlphaFold monomer V2.0 prediction for mitogen-activated protein kinase kinase kinase 14… · a predicted model of the same protein · chain B against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q99558
Elsewhere: RCSB PDB 6WPP · PDBe 6WPP · UniProt Q99558

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