MolNFT v1 · #168720 · protein
Proton-pumping mutant of mastigocladopsis repens rhodopsin chloride pump
6WP8 · Proton-pumping rhodopsin chloride pump: “Proton-pumping mutant of mastigocladopsis repens rhodopsin chloride pump”. X-ray diffraction, 1 ligand (RET), 2 pockets (best druggability 0.80). MolNFT v1 #168720 on GenesisL1: 3D structure…
- PDB
- 6WP8
- Type
- protein
- Length
- 222 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Proton-pumping rhodopsin chloride pump
- Ligands
- RET
- Pockets
- 2 · best druggability 0.80
Structure
x-ray diffraction · 1 distinct chain · 82% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Proton-pumping rhodopsin chloride pump | protein | 222 | 82% helix, 3% strand | — |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 128 | 0.80 | 0.97 | 24 | RET |
| 2 | 78 | 0.64 | 0.91 | 23 | empty |
Modifications
Observed in the structure: 1 cofactor (retinal Schiff base).
Compared structures
- 6WP8 · Proton-pumping mutant of Mastigocladopsis repens rhodopsin chloride pump · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6WP8 · PDBe 6WP8
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