MolNFT v1 · #168524 · protein
Structure of human TRPA1 in complex with inhibitor gdc-0334
6WJ5: “Structure of human TRPA1 in complex with inhibitor gdc-0334”. Electron microscopy, 1 ligand (LXY). MolNFT v1 #168524 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6WJ5
- Type
- protein
- Length
- 2,248 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- O75762
- Ligands
- LXY
Structure
electron microscopy · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | — | protein | 562 | — | O75762 |
Ligands and binding sites
- LXY · (4R,5S)-4-fluoro-1-[(4-fluorophenyl)sulfonyl]-5-methyl-N-({5-(trifluoromethyl)-2-[2-(trifluoromethyl) pyrimidin-5-yl]pyridin-4-yl}methyl)-L-prolinamide · ligand · 4 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6WJ5 · Structure of human TRPA1 in complex with inhibitor GDC-0334 · the same entry in another collection · chain A against A, TM-score 1.00
- O75762 · AlphaFold monomer V2.0 prediction for transient receptor potential cation channel… · a predicted model of the same protein · chain A against A, TM-score 0.86
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O75762
- Elsewhere: RCSB PDB 6WJ5 · PDBe 6WJ5 · UniProt O75762
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