MolNFT v1 · #168434 · protein
Dupilumab Fab with crystal kappa design complexed with human il-4 receptor
6WGL: “Dupilumab Fab with crystal kappa design complexed with human il-4 receptor”. X-ray diffraction, 1 ligand (NAG). MolNFT v1 #168434 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6WGL
- Type
- protein
- Length
- 616 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P24394
- Ligands
- NAG
Structure
x-ray diffraction · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 222 | — | — |
| B | — | protein | 216 | — | — |
| C | — | protein | 178 | — | P24394 |
Ligands and binding sites
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 5 copies · chains C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6WGL · Dupilumab fab with Crystal Kappa design complexed with human IL-4 receptor · the same entry in another collection · chain A against A, TM-score 1.00
- P24394 · AlphaFold monomer V2.0 prediction for interleukin-4 receptor subunit alpha (P24394) · a predicted model of the same protein · chain C against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P24394
- Elsewhere: RCSB PDB 6WGL · PDBe 6WGL · UniProt P24394
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.