MolNFT v1 · #168288 · protein
Structure of mouse importin alpha- MLH1-R472K nls peptide complex
6WBC · Importin subunit alpha-1: “Structure of mouse importin alpha- MLH1-R472K nls peptide complex”. X-ray diffraction. MolNFT v1 #168288 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6WBC
- Type
- protein
- Length
- 436 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Importin subunit alpha-1; DNA mismatch repair protein MLH1
- UniProt
- P52293, P40692
Structure
x-ray diffraction · 2 distinct chains · 71% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Importin subunit alpha-1 | protein | 426 | 73% helix, 0% strand | P52293 |
| B | DNA mismatch repair protein MLH1 | protein | 10 | 0% helix, 0% strand | P40692 |
Interfaces
1 interface between chains.
- A–B · 808 Ų buried · 19 hydrogen bonds · protein-protein
Compared structures
- 6WBC · Structure of Mouse Importin alpha- MLH1-R472K NLS Peptide Complex · the same entry in another collection · chain A against A, TM-score 1.00
- P40692 · AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MLH1 (P40692) · a predicted model of the same protein · chain B against A, TM-score 0.45
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P52293
- Every structure of UniProt P40692
- Elsewhere: RCSB PDB 6WBC · PDBe 6WBC · UniProt P52293 · UniProt P40692
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