MolNFT v1 · #167672 · protein
Discovery of SARXXXX92, a pan-pim kinase inhibitor, efficacious in a KG1 tumor model
6VRV: “Discovery of SARXXXX92, a pan-pim kinase inhibitor, efficacious in a KG1 tumor model”. X-ray diffraction, 1 ligand (WFY). MolNFT v1 #167672 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6VRV
- Type
- protein
- Length
- 271 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P11309
- Ligands
- WFY
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 271 | — | P11309 |
Ligands and binding sites
- WFY · 4-chloro-1-{(1S)-1-[(3S)-3-fluoropyrrolidin-3-yl]ethyl}-3-methyl-1H-pyrrolo[2,3-b]pyridine-6-carboxamide · ligand · chains A
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6VRV · Discovery of SARxxxx92, a pan-PIM kinase inhibitor, efficacious in a KG1 tumor model · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P11309
- Elsewhere: RCSB PDB 6VRV · PDBe 6VRV · UniProt P11309
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