MolNFT v1 · #167593 · protein

TPX2 residues 7-20 fused to aurora a residues 116-389 C247V + D256N + C319V triple mutant disulfide homodimer in complex with AMP-pnp

6VPI: “TPX2 residues 7-20 fused to aurora a residues 116-389 C247V + D256N + C319V triple mutant disulfide homodimer…”. X-ray diffraction, 2 ligands (ANP, MG). MolNFT v1 #167593 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6VPI
Type: protein
Length: 278 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q9ULW0, O14965
Ligands: ANP, MG

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	278	—	Q9ULW0, O14965

Ligands and binding sites

ANP · Phosphoaminophosphonic acid-adenylate ester · ligand · chains A
MG · Magnesium ion · metal · 2 copies · chains A
MLA · Malonic acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6VPI · TPX2 residues 7-20 fused to Aurora A residues 116-389 C247V + D256N + C319V triple mutant… · the same entry in another collection · chain A against A, TM-score 1.00
O14965 · AlphaFold monomer V2.0 prediction for aurora kinase a (O14965) · a predicted model of the same protein · chain A against A, TM-score 0.89
Q9ULW0 · AlphaFold monomer V2.0 prediction for targeting protein for XKLP2 (Q9ULW0) · a predicted model of the same protein · chain A against A, TM-score 0.14

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9ULW0
Every structure of UniProt O14965
Elsewhere: RCSB PDB 6VPI · PDBe 6VPI · UniProt Q9ULW0 · UniProt O14965

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