TPX2 residues 7-20 fused to aurora a residues 116-389 modified with cacodylate and in complex with AMP-pnp

Structure

x-ray diffraction · 1 distinct chain.

Ligands and binding sites

• ANP · Phosphoaminophosphonic acid-adenylate ester · ligand · chains A
• CL · Chloride ion · ion · 2 copies · chains A
• GOL · Glycerol · additive · 4 copies · chains A
• DTD · Dithiane diol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 6VPH · TPX2 residues 7-20 fused to Aurora A residues 116-389 modified with cacodylate and in… · the same entry in another collection · chain A against A, TM-score 1.00
• O14965 · AlphaFold monomer V2.0 prediction for aurora kinase a (O14965) · a predicted model of the same protein · chain A against A, TM-score 0.81
• Q9ULW0 · AlphaFold monomer V2.0 prediction for targeting protein for XKLP2 (Q9ULW0) · a predicted model of the same protein · chain A against A, TM-score 0.15

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q9ULW0
• Every structure of UniProt O14965
• Elsewhere: RCSB PDB 6VPH · PDBe 6VPH · UniProt Q9ULW0 · UniProt O14965