MolNFT v1 · #1675 · protein

Glutathione S-transferase fused with the nuclear matrix targeting signal of the transcription factor aml-1

1B8X · Protein (aml-1B): “Glutathione S-transferase fused with the nuclear matrix targeting signal of the transcription factor aml-1”. X-ray diffraction, 1 pocket (best druggability 0.45). MolNFT v1 #1675 on GenesisL1: 3D structure…

PDB: 1B8X
Type: protein
Length: 260 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein (aml-1B)
UniProt: P08515
Pockets: 1 · best druggability 0.45

Structure

x-ray diffraction · 1 distinct chain · 37% helix, 5% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein (aml-1B)	protein	260	37% helix, 5% strand	P08515

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	119	0.45	0.77	20	empty

Compared structures

1B8X · Glutathione S-transferase fused with the nuclear matrix targeting signal of the… · the same entry in another collection · chain A against A, TM-score 1.00
P08515 · AlphaFold monomer V2.0 prediction for glutathione S-transferase class-mu 26 kda isozyme… · a predicted model of the same protein · chain A against A, TM-score 0.83

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P08515
Elsewhere: RCSB PDB 1B8X · PDBe 1B8X · UniProt P08515

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